Alcohols and polyols
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Filtered Search Results
Medchemexpress LLC Solangepras | 2254706-21-1 | 99.7% | C24H29F2N5O3 | 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Solangepras (CVN424) is an orally active, brain-penetrant inverse agonist of the orphan G protein-coupled receptor GPR6, developed for preclinical Parkinson's disease research. It exhibits high binding affinity and potent functional activity in cellular assays and is supplied as a solid research compound for laboratory studies.
- Orally active and brain-penetrant small molecule suitable for in vivo studies.
- High affinity GPR6 inverse agonist (Ki ≈ 9.4 nM).
- Potent functional activity (EC50 ≈ 38 nM) in relevant assays.
- Available as a stable solid for bench storage and formulation.
- Provided at high chemical purity for research use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Sp4206 | 515846-21-6 | 97.0% | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small-molecule research inhibitor of the IL-2/IL-2Rα protein-protein interaction. It binds IL-2 with high affinity (Kd = 70 nM) and prevents IL-2 binding to IL-2Rα (Kd = 10 nM). Provided as a high-purity solid or DMSO solution for in vitro and in vivo studies; molecular formula C30H37Cl2N7O6; molecular weight 662.56; purity ~97%.
- Inhibits IL-2/IL-2Rα interaction; binds IL-2 with Kd 70 nM.
- Blocks IL-2 binding to IL-2Rα (reported Kd 10 nM).
- High purity (~96.97%) suitable for research applications.
- Available as solid quantities and 10 mM DMSO solution for ready-to-use formulations.
- Soluble in DMSO (100 mg/mL); multiple in vivo formulation protocols reported.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Medchem Express / Xanomeline (oxalate) / 5mg / 446262841 / HY-13410 / / 141064-23-5 / MFCD12828778 / 371.450 / C16H25N3O5S
Medchem Express / Xanomeline (oxalate) / 5mg / 446262841 / HY-13410 / / 141064-23-5 / MFCD12828778 / 371.450 / C16H25N3O5S
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC ESBA 105-A3098-1MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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ESBA 105 is an antibody targeting tumor necrosis factor (TNF) It has an efficient intraocular penetration to anterior and posterior region of eye MW 145 14 KD
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Glucotropaeolin potassium | 5115-71-9 | MFCD00153006 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Glucotropaeolin potassium is a glucosinolate naturally found in cruciferous vegetables. This compound has been observed to cause a moderate decrease in spontaneous DNA damage in animals and is intended for various research applications, particularly in studies involving DNA synthesis and damage.
- Naturally found in cruciferous vegetables
- Causes a moderate decrease in spontaneous DNA damage in animals
- Intended for research use only
- Classified as an alkaloid and glucosinolate
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Medchemexpress LLC AD 01 | 959961-23-0 | 100.0% | 2703.94 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AD 01 is a 24 amino acid peptide of FKBPL (FK506-binding protein like) that possesses potent anti-angiogenic activity. It binds to the CD44 receptor and inhibits tumor cell migration in a CD44 dependent manner. This product is for research use only.
- Purity: 99.98%
- CAS number: 959961-23-0
- Molecular weight: 2703.94
- Molecular formula: C115H187N33O42
- Appearance: Solid
- Color: White to off-white
- Sequence: Gln-Ile-Dir-Gln-Gln-Pro-Arg-Asp-Pro-Pro-Thr-Glu-Thr-Leu-Glu-Leu-Glu-Val-Ser-Pro-Asp-Pro-Ala-Ser
- Sequence shortening: QIRQQPRDPPTETLELEVSPDPAS
- Up-regulates CD44 expression in vitro
- Exhibits anti-tumor activity in vivo
- Solubility: ≥ 100 mg/mL (36.98 mM) in H2O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ms-444 | 150045-18-4 | MFCD00923100 | 99.5% | 230.22 g·mol⁻¹ | C13H10O4 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MS-444 is a small-molecule inhibitor of myosin light chain kinase (MLCK) and the RNA-binding protein HuR (ELAVL1). It inhibits purified smooth muscle MLCK with an IC50 of approximately 10 μM and produces growth inhibition in multiple colorectal cancer cell lines; it is used in biochemical assays, cell-based studies, and preclinical in vivo research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed Pyridazin3 2H one
Pyridazin-3(2H)-one, 504-30-3, 97%
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Medchemexpress LLC LQZ-7I | 195822-23-2 | 99.78% | 348.35 | 50 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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LQZ-7I is a survivin-targeting inhibitor that inhibits survivin dimerization. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. LQZ-7I has improved cytotoxicity with IC50s of 3.1 μM against C4-2 cells and 4.8 μM against PC-3 cells. In vivo studies showed that LQZ-7I significantly suppresses tumor growth without notable adverse effects on mice.
- Inhibits survivin dimerization
- Orally effective in inhibiting xenograft tumor growth
- Induces survivin loss in tumors
- Cytotoxicity with IC50s of 3.1 μM against C4-2 cells
- Cytotoxicity with IC50s of 4.8 μM against PC-3 cells
- Suppresses tumor growth in animal models
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Medchemexpress LLC PXS-5505 anhydrous | 2409964-23-2 | 99.9% | 353.24 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PXS-5505 anhydrous (LOX-IN-3 dihydrochloride) is an orally active lysyl oxidase (LOX) inhibitor. It is used for research in fibrosis, cancer, and angiogenesis. This compound inhibits bovine LOX and human LOXL2 activities, and has demonstrated efficacy in reducing kidney and lung fibrosis in various animal models.
- Inhibits bovine LOX and human LOXL2 activities
- Exhibits sustained inhibition of LOXL1 and LOXL2
- Less active against SSAO/VAP-1 and MAO-B activities
- Abolishes lysyl oxidase activity in rats
- Reduces kidney fibrosis in unilateral ureteric obstruction (UUO) mice models
- Reduces lung fibrosis in Bleomycin-induced lung fibrosis model in C57Bl/6 mice
- For research use only
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eMolecules Ambeed / 3-Methyl-2-buten-1-ol / 25g / 633658617 / A837946 / / 556-82-1 / MFCD00002916 / 86.134 / C5H10O
Ambeed / 3-Methyl-2-buten-1-ol / 25g / 633658617 / A837946 / / 556-82-1 / MFCD00002916 / 86.134 / C5H10O
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Chem-Impex International, Inc. 3-Phenylpropargyl alcohol | MFCD00040914 | 5G
3-Phenylpropargyl alcohol, MFCD00040914, 5G
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![eMolecules Medchem Express / KEA1-97 / 5mg / 603242305 / HY-114982 / / 2138882-71-8 / [null] / 335.160 / C15H9Cl2FN4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502443211.PNG-250.jpg)
eMolecules Medchem Express / KEA1-97 / 5mg / 603242305 / HY-114982 / / 2138882-71-8 / [null] / 335.160 / C15H9Cl2FN4
Medchem Express / KEA1-97 / 5mg / 603242305 / HY-114982 / / 2138882-71-8 / [null] / 335.160 / C15H9Cl2FN4
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules ChemScene / 8-Chloro-34-dihydroquinolin-2(1H)-one / 100mg / 536805982 / CS-0101668 / 0.000 / 83229-23-6 / MFCD19276419 / 181.620 / C9H8ClNO
ChemScene / 8-Chloro-34-dihydroquinolin-2(1H)-one / 100mg / 536805982 / CS-0101668 / 0.000 / 83229-23-6 / MFCD19276419 / 181.620 / C9H8ClNO
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules Medchem Express / CAY10526 / 5mg / 771358295 / HY-118119 / / 938069-71-7 / [null] / 311.150 / C12H7BrO3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502469589.JPG-250.jpg)
eMolecules Medchem Express / CAY10526 / 5mg / 771358295 / HY-118119 / / 938069-71-7 / [null] / 311.150 / C12H7BrO3S
Medchem Express / CAY10526 / 5mg / 771358295 / HY-118119 / / 938069-71-7 / [null] / 311.150 / C12H7BrO3S
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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